MULTIPLE-SCLEROSIS - REMYELINATION IN ACUTE LESIONS

被引:257
作者
RAINE, CS
WU, E
机构
[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED, DEPT NEUROL, BRONX, NY 10461 USA
[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED, DEPT NEUROSCI, BRONX, NY 10461 USA
[3] YESHIVA UNIV ALBERT EINSTEIN COLL MED, ROSE F KENNEDY CTR MENTAL RETARDAT & HUMAN DEV, BRONX, NY 10461 USA
关键词
CNS REMYELINATION; MULTIPLE SCLEROSIS; OLIGODENDROCYTES;
D O I
10.1097/00005072-199305000-00003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Central nervous system (CNS) remyelination has been found by light and electron microscopy and immunoytochemistry within fresh lesions from four cases of acute and chronic progressive multiple sclerosis (MS). The remyelination was sparse and existed in an edematous parenchyma containing oligodendrocytes, macrophages, hypertrophic astrocytes and inflammatory components, but no fibrillary astrogliosis. It is suggested that this type of CNS remyelination in MS is a transient event. Possible underlying factors are discussed.
引用
收藏
页码:199 / 204
页数:6
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