NUCLEOTIDE-SEQUENCE OF A CDNA-ENCODING MURINE FUMARYLACETOACETATE HYDROLASE

被引：12

作者：

GROMPE, M

ALDHALIMY, M

机构：

[1] Department of Molecular and Medical Genetics, Oregon Health Sciences University, Portland, OR 97201, 3181 Sam Jackson Park Road

来源：

BIOCHEMICAL MEDICINE AND METABOLIC BIOLOGY | 1992年 / 48卷 / 01期

关键词：

D O I：

10.1016/0885-4505(92)90044-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hereditary tyrosinemia type I is caused by deficiency of the enzyme fumarylacetoacetate hydrolase (FAH) (EC 3.7.1.2), the final step in tyrosine degradation. We report here the cloning and sequencing of a full length cDNA coding for murine FAH. This cDNA is highly homologous to the previously cloned human and rat genes. © 1992.

引用

页码：26 / 31

页数：6

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