HIGH-RESOLUTION DISTRIBUTION OF MESSENGER-RNA WITHIN THE CYTOSKELETON

被引：31

作者：

BASSELL, GJ ^{[1
]}

机构：

[1] UNIV MASSACHUSETTS,MED CTR,DEPT CELL BIOL,WORCESTER,MA 01655

来源：

JOURNAL OF CELLULAR BIOCHEMISTRY | 1993年 / 52卷 / 02期

关键词：

CYTOSKELETON; INSITU HYBRIDIZATION; MESSENGER RNA LOCALIZATION; MESSENGER RNA-CYTOSKELETAL INTERACTION;

D O I：

10.1002/jcb.240520203

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

It has been well documented that mRNA is associated with the cytoskeleton, and that this relationship is involved in translation and mRNA sorting. The molecular components involved in the attachment of mRNA to the cytoskeleton are only poorly understood. The objective of this research was to directly visualize the interaction of mRNA with the cytoskeleton, with sufficient resolution to identify the filament systems involved. This work required the development of novel in situ hybridization methods for use with electron microscopy.

引用

页码：127 / 133

页数：7

共 26 条

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