COMMITMENT TO SENESCENCE - MODEL FOR FINITE AND INFINITE GROWTH OF DIPLOID AND TRANSFORMED HUMAN FIBROBLASTS IN CULTURE

被引：84

作者：

KIRKWOOD, TBL

HOLLIDAY, R

机构：

[1] NATL INST BIOL STAND & CONTROL,HAMPSTEAD,LONDON NW3 6RB,ENGLAND

[2] NATL INST MED RES,MILL HILL,LONDON NW7 1AA,ENGLAND

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1975年 / 53卷 / 02期

关键词：

D O I：

10.1016/S0022-5193(75)80018-X

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：481 / 496

页数：16

共 23 条

[1] CYTOPLASMIC DNA FROM PETITE COLONIES OF SACCHAROMYCES CEREVISIAE - A HYPOTHESIS ON NATURE OF MUTATION [J].

CARNEVALI, F ;

MORPURGO, G ;

TECCE, G .

SCIENCE, 1969, 163 (3873) :1331-+

[2] CELLULAR SENESCENCE AND DNA-SYNTHESIS - THYMIDINE INCORPORATION AS A MEASURE OF POPULATION AGE IN HUMAN DIPLOID CELLS [J].

CRISTOFALO, VJ ;

SHARF, BB .

EXPERIMENTAL CELL RESEARCH, 1973, 76 (02) :419-427

[3]

CRISTOFALO VJ, 1970, AGING CELL TISSUE CU, P83

[4] SUBCULTIVATIONS, SPLITS, DOUBLINGS, AND GENERATIONS IN CULTURES OF HUMAN DIPLOID FIBROBLASTS [J].

GOOD, PI .

CELL AND TISSUE KINETICS, 1972, 5 (04) :319-&

[5] MITOCHONDRIAL ENZYME ACTIVITY IN SENESCENT AND VIRUS-TRANSFORMED HUMAN FIBROBLASTS [J].

HAKAMI, N ;

PIOUS, DA .

EXPERIMENTAL CELL RESEARCH, 1968, 53 (01) :135-&

[6] LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS [J].

HAYFLICK, L .

EXPERIMENTAL CELL RESEARCH, 1965, 37 (03) :614-&

[7]

HAYFLICK L, 1972, ALTERN ENTWICKLUNG, V4, P1

[8] ERRORS IN PROTEIN SYNTHESIS AND CLONAL SENESCENCE IN FUNGI [J].

HOLLIDAY, R .

NATURE, 1969, 221 (5187) :1224-&

[9]

HOLLIDAY R, 1975, FED PROC, V34, P51

[10] ALTERED ENZYMES IN AGING HUMAN FIBROBLASTS [J].

HOLLIDAY, R ;

TARRANT, GM .

NATURE, 1972, 238 (5358) :26-+

← 1 2 3 →