STRUCTURE AND OVARIAN EXPRESSION OF THE OXYTOCIN GENE IN SHEEP

被引：45

作者：

IVELL, R ^{[1
]}

HUNT, N ^{[1
]}

ABEND, N ^{[1
]}

BRACKMAN, B ^{[1
]}

NOLLMEYER, D ^{[1
]}

LAMSA, JC ^{[1
]}

MCCRACKEN, JA ^{[1
]}

机构：

[1] WORCESTER FDN EXPTL BIOL INC,SHREWSBURY,MA 01545

来源：

REPRODUCTION FERTILITY AND DEVELOPMENT | 1990年 / 2卷 / 06期

关键词：

Corpus luteum; Oestrous cycle;

D O I：

10.1071/RD9900703

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In sheep, the oxytocin gene is highly up-regulated in the ovarian corpus luteum as well as in the hypothalamus. This expression is already elevated on Day 2 of the oestrous cycle, representing 1% of all transcripts in this tissue, and it declines thereafter to low levels after Day 6 of the cycle. In order to study the mechanisms involved in luteal oxytocin gene expression, we have cloned and sequenced the oxytocin gene from the sheep. This gene is closely homologous to other known mammalian oxytocin genes, especially the bovine one, and comparison of the gene promoter regions highlights several blocks of putative control elements. © 1990 CSIRO. All Rights Reserved.

引用

页码：703 / 711

页数：9

共 28 条

[1]

AHLGREN R, 1990, J BIOL CHEM, V265, P3313

[2]

BURBACH JPH, 1990, IN PRESS J NEUROENDO

[3] SUPERCOIL SEQUENCING - A FAST AND SIMPLE METHOD FOR SEQUENCING PLASMID DNA [J].