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EXACERBATION OF HAILEY-HAILEY DISEASE BY HERPES-SIMPLEX VIRUS - DIAGNOSIS BY POLYMERASE CHAIN-REACTION
被引：14
作者：
SCHIRREN, H
SCHIRREN, CG
SCHLUPEN, EM
VOLKENANDT, M
KIND, P
机构：
来源：
HAUTARZT
|
1995年
/
46卷
/
07期
关键词：
HAILEY-HAILEY DISEASE;
BENIGN FAMILIAL PEMPHIGUS;
POLYMERASE CHAIN REACTION;
HERPES SIMPLEX VIRUS;
ELECTRON MICROSCOPY;
HISTOLOGY;
D O I：
10.1007/s001050050289
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
A 49-year-old man suffered from Hailey-Hailey disease for several years. The patient presented with an acute exacerbation of the disease, which did not respond to oral treatment with high doses of glucocorticosteroids. A skin biopsy was taken and the histological examination indicated a viral infection. Herpes simplex virus was confirmed by electron microscopy (negative staining) and polymerase chain reaction (PCR). The PCR presents a sensitive and effective molecular-biological method for the diagnosis of viral infections.
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页码：494 / 497
页数：4
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