AN OVERVIEW OF ENVIRONMENTAL AND TOXICOLOGICAL ASPECTS OF AROMATIC-HYDROCARBONS .3. XYLENE

被引:38
作者
FISHBEIN, L
机构
[1] Department of Health and Human Services, Food and Drug Administration, National Center for Toxicological Research, Jefferson, AR 72079, United States
关键词
HYDROCARBONS - Environmental Impact - INDUSTRIAL HYGIENE;
D O I
10.1016/0048-9697(85)90039-7
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
There is a broad potential for exposure both to industrial workers in the production and use of the xylenes and to the general public. Compared with benzene and toluene, very much less is known of the human health hazards, particularly the chronic effects of xylenes, either as mixed xylenes, as individual isomers or in admixture with other alkylbenzenes. It is of importance to note that coal-based solvents (e. g. , xylene) have been suggested to be possible potent lymphocytic leukemogens, such as benzene, in a limited study of the relationship between lymphocytic leukemia and exposures to benzene and other solvents in the rubber industry. Available animal data on the carcinogenicity of xylene(s) are inadequate to permit an evaluation. Mixed xylenes are currently being investigated in a chronic bioassay by the National Toxicology Program.
引用
收藏
页码:165 / 183
页数:19
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