HYPERINSULINEMIA IN THYROTOXIC HYPOKALEMIC PERIODIC PARALYSIS

被引：54

作者：

LEE, KO ^{[1
]}

TAYLOR, EA ^{[1
]}

OH, VMS ^{[1
]}

CHEAH, JS ^{[1
]}

AW, SE ^{[1
]}

机构：

[1] SINGAPORE GEN HOSP,DEPT CLIN RES,SINGAPORE,SINGAPORE

来源：

LANCET | 1991年 / 337卷 / 8749期

关键词：

D O I：

10.1016/0140-6736(91)91710-C

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To test the hypothesis that there is an abnormal serum insulin response to a carbohydrate load in thyrotoxic hypokalaemic periodic paralysis (THPP), 18 men with THPP and 15 with uncomplicated thyrotoxicosis were studied during an oral glucose tolerance test. The THPP group had significantly higher fasting insulin concentrations (27.6 [3.6] vs 13.4 [1.8] mU/l; p < 0.005) and a higher overall insulin response to oral glucose (p < 0.001 by ANOVA) than the thyrotoxicosis group. There were no significant differences in fasting or stimulated glucose. Hyperinsulinaemia may be an important factor in the precipitation of acute paralysis in THPP.

引用

页码：1063 / 1064

页数：2

共 10 条

[1] EFFECTS OF ORAL AND INTRAVENOUS GLUCOSE LOADING IN THYROTOXICOSIS - STUDIES OF PLASMA GLUCOSE, FREE FATTY ACID, PLASMA INSULIN AND BLOOD PYRUVATE LEVELS [J].