FLUORESCENCE CHARACTERISTICS OF METHOXYCOUMARINS AS NOVEL FLUOROPHORES

被引：37

作者：

TAKADATE, A ^{[1
]}

MASUDA, T ^{[1
]}

MURATA, C ^{[1
]}

TANAKA, T ^{[1
]}

IRIKURA, M ^{[1
]}

GOYA, S ^{[1
]}

机构：

[1] KUMAMOTO UNIV,FAC SCI,KUMAMOTO 862,JAPAN

来源：

ANALYTICAL SCIENCES | 1995年 / 11卷 / 01期

关键词：

METHOXYCOUMARIN; FLUOROPHORE; FLUORESCENCE REAGENT; FLUORESCENCE EMISSION MECHANISM; INTRAMOLECULAR CHARGE-TRANSFER;

D O I：

10.2116/analsci.11.97

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The fluorescence characteristics of various methoxycoumarin fluorophores for the development of fluorescence reagents were examined in relation to their structures. The fluorescence emission mechanisms were also considered from the viewpoint of the intramolecular charge-transfer (CT) between methoxyl substituents and the coumarin ring. The arrangement of 6-methoxyl and 3-acetyl group pairs on the coumarin ring significantly contributed to the fluorescence enhancement through the intramolecular CT. We found that the structural features of methoxycoumarins required for intense fluorescence are to hold both diether bonds at the 6- and 7-positions and an electron-withdrawing group at the 3-position, as shown in 3-acetyl-6,7-dimethoxycoumarin with 0.52 in quantum yield.

引用

页码：97 / 101

页数：5

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