MODIFICATION OF PHOSPHATIDYLCHOLINE-OPIATES INTERACTION BY DIFFERENT BUFFERS

被引：2

作者：

ALSINA, MA ^{[1
]}

ANTON, JMG ^{[1
]}

BUSQUETS, MA ^{[1
]}

ARNAIZ, A ^{[1
]}

REIG, F ^{[1
]}

机构：

[1] CSIC,RES COUNCIL,PEPTIDES LAB,BARCELONA,SPAIN

来源：

COLLOID AND POLYMER SCIENCE | 1990年 / 268卷 / 02期

关键词：

binding; ionic strength; Monolayers; opiates;

D O I：

10.1007/BF01513195

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The influence of subphase composition and ionic strength on the interaction between opiate molecules and phosphatidylcholine has been studied. Results show that a neutral pH favours the penetration of opiate molecules in phosphatidylcholine monolayers, but the ionic strength and the chemical nature of buffer components affect also greatly these interactions. The results could explain, in part the differences in opioid binding values observed for different buffers. © 1990 Steinkopff.

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页码：163 / 166

页数：4

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