ADVERSE REACTIONS TO DRUGS AS A CAUSE OF ADMISSIONS TO A GENERAL TEACHING HOSPITAL IN HONG-KONG

被引：37

作者：

CHAN, TYK

CHAN, JCN

TOMLINSON, B

CRITCHLEY, JAJH

机构：

[1] Department of Clinical Pharmacology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories

来源：

DRUG SAFETY | 1992年 / 7卷 / 03期

关键词：

D O I：

10.2165/00002018-199207030-00008

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

To determine the pattern of and the risk factors for adverse drug reactions (ADRs) in Hong Kong, a prospective study of acute admissions to 2 general medical wards at the Prince of Wales Hospital was undertaken. Of the 1701 admissions included in this study, 74 (4.4%) were attributed to ADRs. Sulphonylureas, nonsteroidal anti-inflammatories (NSAIDs) and insulin accounted for 61% of cases. The most frequent ADRs were hypoglycaemia (43%) and gastrointestinal haemorrhage (29.7%). Both old age and impaired renal function appear to be important risk factors for ADRs. In such situations, careful dose adjustment, use of an alternative drug or total avoidance may be necessary. Particular attention should be given to oral hypoglycaemic drugs and NSAIDs.

引用

页码：235 / 240

页数：6

共 17 条

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