TRITERPENOIDS, TOCOTRIENOLS AND XANTHONES FROM THE BARK OF CRATOXYLUM-COCHINCHINENSE

A novel bicyclic triterpenoid, polypoda-8(26),13,17,21-tetraen-3beta-ol, as well as friedelin, three known tocotrienols, four known xanthones (mangostin, beta-mangostin, garcinone D and tovophyllin A) and the previously unreported 2-geranyl-1,3,6-trihydroxy-4-(3,3-dimethylallyl)-xanthone and cratoxylone (1,3,6-trihydroxy-2-(3-hydroxy-3-methylbutyl)-7-methoxy-8-(3,3-dimethylallyl)-xanthone) have been isolated from the bark of Cratoxylum cochinchinense. The structures of the new compounds were determined using a combination of spectroscopic and chemical methods.