CYCLOADDITION REACTIONS OF CARBOHYDRATE-DERIVATIVES .4. SYNTHESIS OF A TETRAHYDROXYINDOLIZIDINE THROUGH A CYCLIC NITRONE PREPARED FROM D-XYLOSE

被引：54

作者：

HERCZEGH, P ^{[1
]}

KOVACS, I ^{[1
]}

SZILAGYI, L ^{[1
]}

VARGA, T ^{[1
]}

DINYA, Z ^{[1
]}

SZTARICSKAI, F ^{[1
]}

机构：

[1] LAJOS KOSSUTH UNIV,DEPT ORGAN CHEM,H-4010 DEBRECEN,HUNGARY

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)77531-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular conjugate addition of the oxime from aldehyde 5 led to the formation of cyclic nitrone 6. 1,3-Dipolar cycloaddition of the latter with methyl acrylate gave the bicyclic 7 with high diastereoselection. Subsequent four-step transformation of 7 resulted in the tetrahydroxyindolizidine derivative 11.

引用

页码：1211 / 1214

页数：4

共 13 条

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