LOW-TEMPERATURE REACTIONS OF TRYPSIN WITH PARA-NITROANILIDE SUBSTRATES - TETRAHEDRAL INTERMEDIATE FORMATION OR ENZYME ISOMERIZATION

被引：7

作者：

COMPTON, PD ^{[1
]}

FINK, AL ^{[1
]}

机构：

[1] UNIV CALIF SANTA CRUZ,DIV NAT SCI,SANTA CRUZ,CA 95064

来源：

BIOCHEMISTRY | 1984年 / 23卷 / 13期

关键词：

D O I：

10.1021/bi00308a022

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：2989 / 2994

页数：6

共 16 条

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[2] KINETICS OF TRYPSIN-CATALYZED HYDROLYSIS OF P-NITROPHENYL ALPHA-N-BENZYLOXYCARBONYL-L-LYSINATE HYDROCHLORIDE
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (21) : 4953 - &
[3] THE DETECTION, ACCUMULATION AND STABILIZATION OF A TETRAHEDRAL INTERMEDIATE IN TRYPSIN CATALYSIS
COMPTON, P
FINK, AL
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 93 (02) : 427 - 431
[4] MECHANISM OF CHYMOTRYPSIN - STRUCTURE, REACTIVITY, AND NONPRODUCTIVE BINDING RELATIONSHIPS
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[J]. BIOCHEMISTRY, 1973, 12 (06) : 1067 - 1074
[5] EQUILIBRIUM AND RATE CONSTANTS FOR INTERCONVERSION OF 2 CONFORMATIONS OF ALPHA-CHYMOTRYPSIN - EXISTENCE OF A CATALYTICALLY INACTIVE CONFORMATION AT NEUTRAL PH
FERSHT, AR
REQUENA, Y
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1971, 60 (02) : 279 - &
[6] CONFORMATIONAL EQUILIBRIA IN ALPHA-CHYMOTRYPSIN AND DELTA-CHYMOTRYPSIN - ENERGETICS AND IMPORTANCE OF SALT BRIDGE
FERSHT, AR
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1972, 64 (02) : 497 - &
[7] Fink A L, 1979, Methods Enzymol, V63, P336
[8] FINK AL, 1974, J BIOL CHEM, V249, P5027
[9] SLOW TRANSITIONS AND HYSTERETIC BEHAVIOR IN ENZYMES
FRIEDEN, C
[J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1979, 48 : 471 - 489
[10] STRUCTURAL BASIS OF ACTIVATION AND ACTION OF TRYPSIN
HUBER, R
BODE, W
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (03) : 114 - 122

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