STEREOSELECTIVE SYNTHESIS OF OPTICALLY PURE GAMMA-FLUORO-BETA-ENAMINOSULFOXIDES AND REDUCTION TO GAMMA-FLUORO-BETA-AMINOSULFOXIDES

被引：22

作者：

BRAVO, P ^{[1
]}

CRUCIANELLI, M ^{[1
]}

ZANDA, M ^{[1
]}

机构：

[1] UNIV LAQUILA,DIPARTIMENTO CHIM INGN CHIM & MAT,I-67010 LAQUILA,ITALY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 17期

关键词：

D O I：

10.1016/0040-4039(95)00422-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The aza-Wittig reaction of phospha-lambda(5)-azenes with optically pure gamma-fluorosubstituted beta-ketosulfoxides leads to the corresponding beta-enaminosulfoxides, which were easily isolated in diastereomerically pure form. The stereoselective reduction of the enamine 3cb afforded the optically pure beta-sulphinyl-amine 5cb in high overall yield.

引用

页码：3043 / 3046

页数：4

共 21 条

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