INVIVO STUDY OF SCLERODERMA BY NONINVASIVE TECHNIQUES

被引：31

作者：

KALIS, B ^{[1
]}

DERIGAL, J ^{[1
]}

LEONARD, F ^{[1
]}

LEVEQUE, JL ^{[1
]}

RICHE, O ^{[1
]}

LECORRE, Y ^{[1
]}

DELACHARRIERE, O ^{[1
]}

机构：

[1] LABS RECH LOREAL,AULNAY SOUS BOIS,FRANCE

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1990年 / 122卷 / 06期

关键词：

D O I：

10.1111/j.1365-2133.1990.tb06267.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Sixteen patients with localized scleroderma (LS) and 11 with progressive systemic sclerosis (PSS) were studied using non-invasive techniques to determine skin thickness, skin extensibility, transcutaneous PO2 and cutaneous blood flow and were compared with normal controls. LS was characterized by a decreased skin extensibility with thickening of the skin in progressive lesions. There was an increase in the cutaneous microcirculation with a decrease in the PO2. In PSS, there was a decrease in the skin extensibility caused by thickening of the skin, but no change in cutaneous microcirculation or PO2 values. These results indicate that skin thickness and extensibility are the most useful parameters in the study of the progression of LS and PSS.

引用

页码：785 / 791

页数：7

共 14 条

[1] MECHANICAL-PROPERTIES AND YOUNGS MODULUS OF HUMAN-SKIN INVIVO [J].