THE EFFECT OF INDUCED-ABORTION ON SUBSEQUENT PREGNANCY OUTCOME

被引:38
作者
FRANK, PI [1 ]
MCNAMEE, R [1 ]
HANNAFORD, PC [1 ]
KAY, CR [1 ]
HIRSCH, S [1 ]
机构
[1] UNIV MANCHESTER,SCH EPIDEMIOL & HLTH STUDIES,CTR OCCUPAT HLTH,MANCHESTER M13 9PT,LANCS,ENGLAND
来源
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 1991年 / 98卷 / 10期
关键词
D O I
10.1111/j.1471-0528.1991.tb15340.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective - To investigate the effect of induced abortion on the outcome of the next pregnancy. Design - Long-term prospective controlled cohort study. Setting - Joint Royal College of General Practitioners/Royal College of Obstetricians and Gynaecologists study based in general practice in England, Scotland and Wales. Subjects - 1311 women whose recruitment pregnancy had ended in induced abortion (the abortion group) and 2131 women whose recruitment pregnancy had a natural conclusion (the non-abortion group). Main outcome measures - Non-viable outcome (spontaneous or missed miscarriage, ectopic pregnancy or stillbirth), birthweight, length of gestation. Results - Induced abortion was not materially associated with any of the three measures of adverse outcome. Compared with the non-abortion group the relative risk of a non-viable outcome in the abortion group was 1.01 (95% CI 0.81 to 1.27). In the abortion group birthweight was an average 23 g lighter (95% CI -76 g to +30 g) and length of gestation an average 0.9 days shorter (95% CI -2.2 days to +0.4 days) than in the non-abortion group. Women who had their abortions in NHS premises had an increased risk of a non-viable outcome (RR 2.55, 95% CI 1.31 to 4.94) and had babies with significantly lower mean birthweight (-119 g, 95% CI -233 g to +5 g) compared with those who obtained their operations in the private sector. Women whose abortion had been carried out by a consultant had the lowest risk of non-viable outcome. Although these differences remained after adjustment for a number of important variables, it is possible that factors not measured in the present study, such as economic status and occupation, played a contributory role. Conclusion - Overall, induced abortion was not associated with any important effect on the three measures of adverse outcome in the subsequent pregnancy.
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页码:1015 / 1024
页数:10
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