ANTENATAL DIAGNOSIS AND SURGICAL-MANAGEMENT OF CONGENITAL CYSTIC ADENOMATOID MALFORMATION OF THE LUNG

被引:26
作者
TAGUCHI, T
SUITA, S
YAMANOUCHI, T
NAGANO, M
SATOH, S
KOYANAGI, T
NAKANO, H
机构
[1] Departments of a Pediatric Surgery, Fukuoka
[2] Obstetrics and Gynecology, Kyushu University, Fukuoka
[3] Maternity and Perinatal Care Unit, Kyushu University Hospital, Fukuoka
关键词
CONGENITAL CYSTIC ADENOMATOID MALFORMATION; LUNG; PRENATAL DIAGNOSIS; HYDROPS FETALIS; PULMONARY HYPOPLASIA; FETAL SURGERY; NEONATAL SURGERY; LOBECTOMY;
D O I
10.1159/000264265
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
We experienced 12 cases of congenital cystic adenomatoid malformation of the lung (CCAM) including 6 cases diagnosed antenatally. They were classified into three groups according to the clinical manifestations. Group A was associated with hydrops fetalis (n = 3), group B presented with respiratory distress symptoms after birth (n = 6), and group C showed no respiratory symptoms (n = 3). All cases of group A were lost because of hydrops and respiratory failure due to pulmonary hypoplasia. Because a compression of the mass is thought to be a cause of hydrops, this group is considered to be a good indication for fetal treatment. All cases of group B showed progressive respiratory symptoms a few days after birth which were successfully treated surgically. In 2 of 3 cases of group C, the lesions decreased in size both antenatally and postnatally. We conclude that serial sonographic evaluations for fetal CCAM are important. If the fetus develops hydrops, fetal surgery is to be considered. If not, however, fetal surgery should not be done, because some lesions can shrink in size, or even disappear, while others can be treated successfully after birth by lobectomy or even segmentectomy.
引用
收藏
页码:400 / 407
页数:8
相关论文
共 12 条
[1]  
Stocker J.T., Madewell J.E., Drake R.M., Congenital cystic adenomatoid malformation of the lung, Hum Pathol, 8, pp. 155-171, (1977)
[2]  
Kwittken J., Reiner L., Congenital cystic malformation of the lung, Pediatrics, 30, pp. 759-768, (1962)
[3]  
Adzick N.S., Harrison M.R., Glick P.L., Golbus M.S., Erson R.L., Mahony B.S., Callen P.W., Hirsch J.H., Luthy D.A., Filly R.A., Delorimier A.A., Fetal cystic adenomatoid malformation: Prenatal diagnosis and natural history, J Pediatr Surg, 20, (1985)
[4]  
Avni E.F., Vanderelst A., Van Gans- Berke D., Schils J., Rodesch F., Antenatal diagnosis of pulmonary tumors: Report of two cases, Pediatr Radiol, 16, pp. 190-192, (1986)
[5]  
Clark S.L., Vitale D.J., Minton S.D., Stoddard R.A., Sabey P.L., Successful fetal therapy for cystic adenomatoid malformation associated with second-trimester hydrops, Am J Obstet Gynecol, 157, pp. 294-295, (1987)
[6]  
Nugent C.E., Hayashi R.H., Rubin J., Prenatal treatment of type I congenital cystic adenomatoid malformation by intrauterine fetal thoracentesis, J Clin Ultrasound, 17, (1989)
[7]  
Adzick N.S., Harrison M.R., Flake A.W., Howell U., Golbus M.S., Filly R.A., The UCSF Fetal Treatment Center: Fetal surgery for cystic adenomatoid malformation of the lung, J Pediatr Surg, 28, pp. 806-812, (1993)
[8]  
Dumez Y., Mandelbrot L., Radunovic N., Revillon Y., Dommergues M., Aubry M.C., Aubry J.P., Narcy F., Prenatal management of congenital cystic adenomatoid malformation of the lung, J Pediatr Surg, 28, (1993)
[9]  
Benjamin D.R., Cahill J.L., Bron- chioalveolar carcinoma of the lung and congenital cystic adenomatoid malformation, Am J Clin Pathol, 95, pp. 889-892, (1991)
[10]  
Ueda K., Gruppo R., Unger F., Martin L., Bove K., Rhabdomyosarcoma of lung arising in a congenital cystic adenomatoid malformation, Cancer, 40, pp. 383-388, (1977)