A NOVEL METHOD OF CONJUGATION OF DAUNOMYCIN WITH ANTIBODY WITH A POLY-L-GLUTAMIC ACID-DERIVATIVE AS INTERMEDIATE-DRUG CARRIER - AN ANTI-ALPHA-FETOPROTEIN ANTIBODY-DAUNOMYCIN CONJUGATE

被引：34

作者：

KATO, Y

UMEMOTO, N

KAYAMA, Y

FUKUSHIMA, H

TAKEDA, Y

HARA, T

TSUKADA, Y

机构：

[1] TEIJIN INST BIOMED RES, DEPT MED CHEM & BIOCHEM, HINO, TOKYO 191, JAPAN

[2] HOKKAIDO UNIV, SCH MED, DEPT BIOCHEM, SAPPORO, HOKKAIDO 060, JAPAN

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1984年 / 27卷 / 12期

关键词：

D O I：

10.1021/jm00378a013

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1602 / 1607

页数：6

共 28 条

[1] TOTAL SYNTHESIS OF ANTITUMOR ANTIBIOTIC DAUNORUBICIN - COUPLING OF SUGAR AND AGLYCONE [J].

ACTON, EM ;

FUJIWARA, AN ;

HENRY, DW .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (06) :659-660

[2] POLYPEPTIDES .3. THE SYNTHESIS OF HIGH MOLECULAR WEIGHT POLY-GAMMA-BENZYL-L-GLUTAMATES [J].

BLOUT, ER ;

KARLSON, RH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1956, 78 (05) :941-946

[3]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[4] LYSOSOMOTROPIC AGENTS [J].

DEDUVE, C ;

DEBARSY, T ;

POOLE, B ;

TROUET, A ;

TULKENS, P ;

VANHOOF, F .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (18) :2495-+

[5] POLYPEPTIDES .4. THE MOLECULAR WEIGHT, CONFIGURATION AND ASSOCIATION OF POLY-GAMMA-BENZYL-L-GLUTAMATE IN VARIOUS SOLVENTS [J].

DOTY, P ;

BRADBURY, JH ;

HOLTZER, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1956, 78 (05) :947-954

[6] TISSUE SULFHYDRYL GROUPS [J].

ELLMAN, GL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) :70-77

[7] SELECTIVE CYTO-TOXICITY AGAINST HUMAN-TUMOR CELLS BY A VINDESINE MONOCLONAL-ANTIBODY CONJUGATE [J].

EMBLETON, MJ ;

ROWLAND, GF ;

SIMMONDS, RG ;

JACOBS, E ;

MARSDEN, CH ;

BALDWIN, RW .

BRITISH JOURNAL OF CANCER, 1983, 47 (01) :43-49

[8] SOME MACROMOLECULAR PROPERTIES OF POLY(ALPHA)-L-GLUTAMIC ACID) RANDOM COILS [J].

HAWKINS, RB ;

HOLTZER, A .

MACROMOLECULES, 1972, 5 (03) :294-&

[9] PURIFICATION OF SPECIFIC ANTIBODY TO ALPHA-FETOPROTEIN AND ITS IMMUNOLOGICAL EFFECT ON CANCER-CELLS [J].

HIRAI, H ;

TSUKADA, Y ;

HARA, A ;

HIBI, N ;

NISHI, S ;

WEPSIC, HT ;

KOJI, T ;

ISHII, N .

JOURNAL OF CHROMATOGRAPHY, 1981, 215 (1-3) :195-210

[10]

HURWITZ E, 1975, CANCER RES, V35, P1175

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