1-ETHYNYLPYRENE, A SUICIDE INHIBITOR OF CYTOCHROME-P-450 DEPENDENT BENZO[A]PYRENE HYDROXYLASE-ACTIVITY IN LIVER-MICROSOMES

被引：56

作者：

GAN, LSL ^{[1
]}

ACEBO, AL ^{[1
]}

ALWORTH, WL ^{[1
]}

机构：

[1] TULANE UNIV,DEPT CHEM,NEW ORLEANS,LA 70118

来源：

BIOCHEMISTRY | 1984年 / 23卷 / 17期

关键词：

D O I：

10.1021/bi00312a006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：3827 / 3836

页数：10

共 33 条

[1] INHIBITION BY 17-ALPHA-ETHINYL ESTRADIOL OF BENZO[A]-PYRENE METABOLISM IN ISOLATED ADULT-RAT HEPATOCYTES [J].

BENREKASSA, J ;

DECLOITRE, F .

BIOCHEMICAL PHARMACOLOGY, 1983, 32 (02) :347-353

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3] DEGRADATION OF DIFFERENT FORMS OF CYTOCHROME-P-450 INVIVO BY FLUROXENE AND ALLYL-ISO-PROPYLACETAMIDE [J].

BRADSHAW, JJ ;

ZIMAN, MR ;

IVANETICH, KM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 85 (03) :859-866

[4]

DEMONTELLANO O, 1980, J AM CHEM SOC, V102, P7373

[5] DESTRUCTION OF CYTOCHROME-P-450 BY ALLYLISOPROPYLACETAMIDE IS A SUICIDAL PROCESS [J].

DEMONTELLANO, PRO ;

MICO, BA .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1981, 206 (01) :43-50

[6]

DEMONTELLANO PRO, 1983, ANNU REV PHARMACOL, V23, P481

[7] CYTOCHROME-P-450 INACTIVATION - STRUCTURE OF THE PROSTHETIC HEME ADDUCT WITH PROPYNE [J].

DEMONTELLANO, PRO ;

KUNZE, KL .

BIOCHEMISTRY, 1981, 20 (25) :7266-7271

[8] DESTRUCTION OF CYTOCHROME-P-450 BY VINYL FLUORIDE, FLUROXENE, AND ACETYLENE - EVIDENCE FOR A RADICAL INTERMEDIATE IN OLEFIN OXIDATION [J].

DEMONTELLANO, PRO ;

KUNZE, KL ;

BEILAN, HS ;

WHEELER, C .

BIOCHEMISTRY, 1982, 21 (06) :1331-1339

[9] EPOXIDE HYDRASE - STRUCTURE-ACTIVITY-RELATIONSHIPS OF INVITRO STIMULATORS OF MICROSOMAL ACTIVITY [J].

GANU, VS ;

ALWORTH, WL .

BIOCHEMISTRY, 1978, 17 (14) :2876-2881

[10] PURIFICATION AND CHARACTERIZATION OF LIVER MICROSOMAL CYTOCHROMES-P-450 - ELECTROPHORETIC, SPECTRAL, CATALYTIC, AND IMMUNOCHEMICAL PROPERTIES AND INDUCIBILITY OF 8 ISOZYMES ISOLATED FROM RATS TREATED WITH PHENOBARBITAL OR BETA-NAPHTHOFLAVONE [J].

GUENGERICH, FP ;

DANNAN, GA ;

WRIGHT, ST ;

MARTIN, MV ;

KAMINSKY, LS .

BIOCHEMISTRY, 1982, 21 (23) :6019-6030

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