MAYTANSINE INHIBITS NUCLEOTIDE BINDING AT THE EXCHANGEABLE SITE OF TUBULIN

被引：54

作者：

HUANG, AB ^{[1
]}

LIN, CM ^{[1
]}

HAMEL, E ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,DEV THERAPEUT PROGRAM,PHARMACOL & EXPTL THERAPEUT LAB,BETHESDA,MD 20205

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1985年 / 128卷 / 03期

关键词：

D O I：

10.1016/0006-291X(85)91073-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1239 / 1246

页数：8

共 21 条

[1]

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[4]

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[5]

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[8] INTERACTIONS OF COMBRETASTATIN, A NEW PLANT-DERIVED ANTIMITOTIC AGENT, WITH TUBULIN [J].

HAMEL, E ;

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[9] SEPARATION OF ACTIVE TUBULIN AND MICROTUBULE-ASSOCIATED PROTEINS BY ULTRACENTRIFUGATION AND ISOLATION OF A COMPONENT CAUSING THE FORMATION OF MICROTUBULE BUNDLES [J].

HAMEL, E ;

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BIOCHEMISTRY, 1984, 23 (18) :4173-4184

[10] DEOXYGUANOSINE NUCLEOTIDE ANALOGS - POTENT STIMULATORS OF MICROTUBULE NUCLEATION WITH REDUCED AFFINITY FOR THE EXCHANGEABLE NUCLEOTIDE SITE OF TUBULIN [J].

HAMEL, E ;

LUSTBADER, J ;

LIN, CM .

BIOCHEMISTRY, 1984, 23 (22) :5314-5325

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