5-AMINO-6-HYDROXY-3,4,5,6-TETRAHYDROPYRAN-2-ONE (HAT) - A STABLE, CYCLIC FORM OF GLUTAMATE 1-SEMIALDEHYDE, THE NATURAL PRECURSOR FOR TETRAPYRROLES

被引：3

作者：

JORDAN, PM

CHEUNG, KM

SHARMA, RP

WARREN, MJ

机构：

[1] School of Biological Sciences, Queen Mary and Westfield College, University of London, London, E1 4NS, Mile End Road

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)77521-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Glutamate 1-semialdehyde is shown to exist in a cyclic form, 5-amino-6-hydroxy-3,4,5,6-tetrahydropyran-2-one (HAT), which explains its unexpectedly high stability for an alpha-aminoaldehyde. It is proposed that the cyclic form is the actual intermediate in the biosynthesis of tetrapyrroles.

引用

页码：1177 / 1180

页数：4

共 6 条

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[4] DELTA-AMINOLEVULINATE SYNTHESIS IN GREENING BARLEY .5. THE STRUCTURE OF GLUTAMATE 1-SEMIALDEHYDE [J].

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[5]

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[6]

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