STEREOSELECTIVE SYNTHESES OF D-RIBO-PHYTOSPHINGOSINE AND L-LYXO-PHYTOSPHINGOSINE

被引：32

作者：

LI, YL ^{[1
]}

MAO, XH ^{[1
]}

WU, YL ^{[1
]}

机构：

[1] CHINESE ACAD SCI,SHANGHAI INST ORGAN CHEM,STATE KEY LAB BIOORGAN & NAT PROD CHEM,SHANGHAI 200032,PEOPLES R CHINA

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1995年 / 12期

关键词：

D O I：

10.1039/p19950001559

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

D-ribo-Phytosphingosine has been synthesized from D-galactose via the key intermediate 5, itself prepared by stereoselective prop-2-ynylation with prop-2-ynyl bromide and zinc, and L-lyxo-phytosphingosine has been synthesized from D-xylose via the key intermediate 18, itself prepared by a CBr4-Ph(3)P-Zn Wittig reaction and debromination. These key chiral intermediates, 5 and 18, have potential as intermediates for the synthesis of other phytosphigosine derivatives.

引用

页码：1559 / 1563

页数：5

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