NEW BRIAREIN DITERPENES FROM THE CARIBBEAN GORGONIANS ERYTHROPODIUM-CARIBAEORUM AND BRIAREUM SP

被引：73

作者：

PORDESIMO, EO ^{[1
]}

SCHMITZ, FJ ^{[1
]}

CIERESZKO, LS ^{[1
]}

HOSSAIN, MB ^{[1
]}

VANDERHELM, D ^{[1
]}

机构：

[1] UNIV OKLAHOMA,DEPT CHEM & BIOCHEM,NORMAN,OK 73019

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 07期

关键词：

D O I：

10.1021/jo00007a020

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Seven new erythrolides (3-9) and the known briarein diterpenes erythrolide A (1) and erythrolide B (2) have been isolated from the gorgonian Erythropodium caribaeorum collected in the U.S. Virgin Islands and Jamaica. A Briareum sp. of gorgonian yielded nine new briarein diterpenes (10-18), which have been named briareolides. The structures of these compounds were determined by spectroscopic methods, especially one- and two-dimensional NMR. The structure and absolute stereochemistry of briareolide B (11) was determined by X-ray crystallographic analysis. Some of the briareolides have displayed antiinflammatory activity.

引用

页码：2344 / 2357

页数：14

共 30 条

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BARTHOLOME C, 1974, THESIS U LIBRE BRUXE

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