FLOPPING POLYPEPTIDE-CHAINS AND SULEIKAS SUBTLE IMPERFECTIONS - ANALYSIS OF VARIATIONS IN THE ELECTRON MICROGRAPH OF A PURPLE MEMBRANE CRYSTAL

被引:11
作者
FRANK, J
CHIU, W
HENDERSON, R
机构
[1] SUNY ALBANY,DEPT BIOMED SCI,ALBANY,NY 12222
[2] BAYLOR COLL MED,VERNA & MARRS MCLEAN DEPT BIOCHEM,HOUSTON,TX 77030
[3] MRC,MOLEC BIOL LAB,CAMBRIDGE,ENGLAND
关键词
D O I
10.1016/0304-3991(93)90244-R
中图分类号
TH742 [显微镜];
学科分类号
摘要
Patch averaging, a method of data analysis combining correlation averaging with multivariate statistical analysis, was applied to a high-resolution image of a purple membrane thin crystal. The observed variational patterns fall in two categories: non-crystallographic, related to small electron-optical distortions of the microscope, and crystallographic. conceivably related to variations in the locations of flexible segments of the polypeptide chain on the surface of the membrane.
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页码:387 / 396
页数:10
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