THE INTERACTION OF RH(II) AND RH(III) WITH DNA

被引：23

作者：

TSELEPIKALOULI, E

KATSAROS, N

机构：

[1] Institute of Physical Chemistry, National Research Center Democritos, Athens

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1990年 / 40卷 / 02期

关键词：

D O I：

10.1016/0162-0134(90)80042-V

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The interaction of Rh2(II)(acetate)4, cis-[Rh(III)(en)2Cl2]Cl (en = ethylenediamine) and [Rh(III) (NH3)5Cl]Cl2 with calf thymus DNA has been studied at various r values (r = [Mn+] [DNA - P]) and interaction times. Electronic spectra, melting and cooling curves and sedimentation data indicate no interaction of the acetate complex with DNA, except in the case of a high r value and long interaction time. The other two complexes have been found to interact with the phosphate groups, thus stabilizing the macromolecule. © 1990.

引用

页码：95 / 102

页数：8

共 15 条

[1] CATION EFFECTS ON DENATURATION OF DNA [J].