ELEVATED LEVELS OF NONESTERIFIED FATTY-ACIDS IN THE MYOCARDIUM OF ALLOXAN DIABETIC RATS

被引：15

作者：

CHATTOPADHYAY, J ^{[1
]}

THOMPSON, EW ^{[1
]}

SCHMID, HHO ^{[1
]}

机构：

[1] UNIV MINNESOTA,HORMEL INST,801 16TH AVE NE,AUSTIN,MN 55912

来源：

LIPIDS | 1990年 / 25卷 / 06期

关键词：

D O I：

10.1007/BF02544338

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Myocardial nonesterified fatty acids (NEFA) increase markedly within the first two days after the induction of insulin-dependent diabetes mellitus in rats by intravenous injection of alloxan. After initial variability, NEFA levels in diabetic hearets remain constant at approximately 450 nmol/g tissue (16 nmol/gmmol lipid P), which is about three times higher than that in control hearts. Nonesterified linoleic acid is significantly increased in diabetic heart whereas both arachidonic and docosahexaenoic acids are decreased compared to controls. © 1990 American Oil Chemists' Society.

引用

页码：307 / 310

页数：4

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