SYSTEMATIC SEARCH FOR SUITABLE 2-PHASE SOLVENT SYSTEMS FOR HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY

被引：170

作者：

OKA, F ^{[1
]}

OKA, H ^{[1
]}

ITO, Y ^{[1
]}

机构：

[1] NHLBI,TECH DEV LAB,BETHESDA,MD 20892

来源：

JOURNAL OF CHROMATOGRAPHY | 1991年 / 538卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(01)91626-7

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We have introduced two series of two-phase solvent systems which facilitate the systematic search for the solvent systems suitable for high-speed counter-current chromatography. The n-hexane-ethyl acetate-n-butanol-methanol-water systems provide a broad range of hydrophobicity, while the chloroform-methanol-water systems are extremely useful for separations of various natural products with moderate hydrophobicity. The practical use of these solvent series was demonstrated with several test samples which include dinitrophenyl amino acids, S-triazine herbicides, indole auxins, and non-ionic organic solvents.

引用

页码：99 / 108

页数：10

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