Segmentation of intravascular ultrasound images: A knowledge-based approach

被引:171
作者
Sonka, M
Zhang, XM
Siebes, M
Bissing, MS
DeJong, SC
Collins, SM
McKay, CR
机构
[1] UNIV IOWA, DEPT INTERNAL MED, IOWA CITY, IA 52242 USA
[2] UNIV IOWA, DEPT BIOMED ENGN, IOWA CITY, IA 52242 USA
[3] UNIV IOWA, DEPT RADIOL, IOWA CITY, IA 52242 USA
关键词
D O I
10.1109/42.476113
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Intravascular ultrasound imaging of coronary arteries provides important information about coronary lumen, wall, and plaque characteristics. Quantitative studies of coronary atherosclerosis using intravascular ultrasound and manual identification of wall and plaque borders are limited by the need for observers with substantial experience and the tedious nature of manual border detection. We have developed a method for segmentation of intravascular ultrasound images that identifies the internal and external elastic laminae and the plaque-lumen interface. The border detection algorithm was evaluated in a set of 38 intravascular ultrasound images acquired from fresh cadaveric hearts using a 30 MHz imaging catheter. To assess the performance of our border detection method we compared five quantitative measures of arterial anatomy derived from computer-detected borders with measures derived from borders manually defined by expert observers. Computer-detected and observer-defined lumen areas correlated very well (r = 0.96, y = 1.02x+ 0.52), as did plaque areas (r = 0.95, y = 1.07x- 0.48), and percent area stenosis (r = 0.93, y = 0.99x- 1.34.) Computer-derived segmental plaque thickness measurements were highly accurate. Our knowledge-based intravascular ultrasound segmentation method shows substantial promise for the quantitative analysis of in vivo intravascular ultrasound image data.
引用
收藏
页码:719 / 732
页数:14
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