ANALYSIS OF PROGNOSTIC FACTORS AND PROPOSAL OF A NEW CLASSIFICATION FOR NASOPHARYNGEAL CANCER

被引:26
作者
GRANDI, C
BORACCHI, P
MEZZANOTTE, G
SQUADRELLI, M
MARUBINI, E
MOLINARI, R
机构
[1] UNIV MILAN,IST NAZL STUDIO & CURA TUMORI,I-20122 MILAN,ITALY
[2] UNIV MILAN,IST STAT MED & BIOMETRIA,I-20122 MILAN,ITALY
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 1990年 / 12卷 / 01期
关键词
D O I
10.1002/hed.2880120105
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
A retrospective analysis was performed on 410 patients with nasopharyngeal carcinoma of squamous or undifferentiated histotype. All patients were classified according to the classification of the American Joint Committee for Cancer Staging and End‐Results Reporting (AJC) and to that of the International Union Against Cancer (UICC, Geneva, 1978). The following prognostic factors were investigated by means of a Weibull multiple regression model: sex, age, histology, primary tumor extent, and nodal metastasis extent. With the exception of sex, all factors significantly influenced survival. With regards to nodal extent, only the level of the involved nodes was a significant variable. Both AJC and UICC classifications, when applied to the entire series of patients, appeared to be unsatisfactory. The authors propose an alternative classification based on a prognostic scoring system directly derived from the Weibull model. Copyright © 1990 Wiley Periodicals, Inc., A Wiley Company
引用
收藏
页码:31 / 40
页数:10
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