9 POLYMORPHIC MARKERS CHARACTERIZED BY POLYMERASE CHAIN-REACTION TECHNIQUES FORM 2 LINKAGE GROUPS ON RAT CHROMOSOME-8

被引：10

作者：

MATHERN, P ^{[1
]}

GOLDMUNTZ, EA ^{[1
]}

DU, Y ^{[1
]}

ZHA, H ^{[1
]}

CASH, JM ^{[1
]}

CROFFORD, LJ ^{[1
]}

WILDER, RL ^{[1
]}

REMMERS, EF ^{[1
]}

机构：

[1] NIAMS,ARTHRITIS & RHEUMATISM BRANCH,BETHESDA,MD 20892

来源：

CYTOGENETICS AND CELL GENETICS | 1994年 / 66卷 / 04期

关键词：

D O I：

10.1159/000133713

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Five genes and four anonymous polymorphic markers, forming two linkage groups, were mapped in Fz intercross progeny of F344/N x LEW/N rats using polymerase chain reaction (PCR) techniques. Both linkage groups were assigned to rat chromosome 8 because they contained genetic loci previously mapped to this chromosome. The first group was comprised of markers for three anonymous loci and two gene loci, thymus cell antigen-1 (Thy1) and tropoelastin (Eln). The second group was comprised of markers for one anonymous locus and three gene loci, cellular retinol binding protein II (Rbp2), matrin F/G (Matr1), and acyl-peptide hydrolase (Apeh). Seven markers (identified by simple sequence repeat associated length polymorphisms) were characterized in an additional 13 inbred rat strains (ACI/N, BN/SsN, BUF/N, LER/N, LOU/ MN, MNR/N, MR/N, SHR/N, SR/Jr, SS/Jr, WBB1/N, WBB2/N, and WKY/N). Two to six alleles were detected for each marker. The reported markers should facilitate genetic mapping and monitoring of inbred rat strains.

引用

页码：283 / 286

页数：4

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