SYNTHESIS OF (ETA-5-C5ME5)RU(ETA-6-TRYPTAMINE)(CF3SO3) COMPLEXES - CHEMOSPECIFIC ETA-6 COORDINATION OF THE (ETA-5-C5ME5)RU+ MOIETY

被引：21

作者：

LOMENZO, SA ^{[1
]}

NOLAN, SP ^{[1
]}

TRUDELL, ML ^{[1
]}

机构：

[1] UNIV NEW ORLEANS,DEPT CHEM,NEW ORLEANS,LA 70148

来源：

ORGANOMETALLICS | 1994年 / 13卷 / 02期

关键词：

D O I：

10.1021/om00014a045

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A series of Cp*Ru(eta6-N(b)-acyltryptamine)OTf and Cp*Ru(eta6-N(b)-CBZ-tryptamine)OTf complexes have been prepared from the reaction of Cp*Ru(CH3CN)3OTf (1) with the corresponding N(b)-acyl-tryptamine and N(b)-CBZ-tryptamine derivatives in THF at ambient reaction conditions under an argon atmosphere. The complexes are air stable and were obtained in high yields (>90%). Cp*Ru(eta6-N(b)-BOC-tryptamine]OTf (10) and Cp*Ru(eta6-N(b)-CBZ-tryptamine)OTf(16) were readily converted into Cp*Ru(eta6-tryptamine)OTf (3) in good yields (61% and 87%, respectively). The kinetic eta6 coordination of the electrophilic Cp*Ru+ moiety was found to be chemospecific for the electron-rich indole nucleus. No competing eta6 coordination was observed at the arene unit of a variety of substituted N(b)-CBZ-tryptamine derivatives.

引用

页码：676 / 681

页数：6

共 25 条

[1] THE SYNTHESIS OF 4-SUBSTITUTED INDOLES VIA ARENETRICARBONYLCHROMIUM(O) COMPLEXES [J].