MICROBIAL RECOGNITION OF TARGET-CELL GLYCOCONJUGATES

被引：276

作者：

KARLSSON, KA

机构：

[1] Department of Medical Biochemistry, S-413 90 Göteborg

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1995年 / 5卷 / 05期

关键词：

D O I：

10.1016/0959-440X(95)80054-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Attachment of microbial protein to host cell-surface carbohydrate is considered essential for successful infection. Information of conceptual interest, including crystal structures of protein-saccharide complexes and convincing models of target membrane penetration, continues to emerge for viruses and bacterial toxins. Other important data relate to therapeutic receptor blockade, through the use of saccharide analogs or vaccines directed against the microbial adhesin.

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页码：622 / 635

页数：14

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