4 NEW BETA-CARBOLINE ALKALOIDS ISOLATED FROM 2 OKINAWAN MARINE SPONGES OF XESTOSPONGIA SP AND HALICLONA SP

被引：72

作者：

KOBAYASHI, M

CHEN, YJ

AOKI, S

IN, Y

ISHIDA, T

KITAGAWA, I

机构：

[1] OSAKA UNIV,FAC PHARMACEUT SCI,SUITA,OSAKA 565,JAPAN

[2] OSAKA UNIV PHARMACEUT SCI,MATSUBARA,OSAKA 580,JAPAN

来源：

TETRAHEDRON | 1995年 / 51卷 / 13期

关键词：

D O I：

10.1016/0040-4020(95)95723-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two new beta-carboline alkaloids, xestomanzamine A (1) and xestomanzamine B (2), and a new manzamine-type alkaloid, manzamine X (3), were isolated as cytotoxic constituents from an Okinawan marine sponge of Xestospongia sp. Another new manzamine-type alkaloid, manzamine Y (4), was isolated from an Okinawan marine sponge of Haliclona sp. The structures of these alkaloids were elucidated on the bases of 2D-NMR and X-ray analyses.

引用

收藏

页码：3727 / 3736

页数：10

相关论文

共 14 条

[1] ON THE BIOSYNTHESIS OF MANZAMINES [J].

BALDWIN, JE ;

WHITEHEAD, RC .

TETRAHEDRON LETTERS, 1992, 33 (15) :2059-2062

[2]

Debaerdemaeker T, 1987, MULTAN87 SYSTEM COMP

[3]

ICHIBA I, 1994, J NAT PRODUCTS, V57, P168

[4] NEW MANZAMINE ALKALOIDS FROM A SPONGE OF THE GENUS XESTOSPONGIA [J].

ICHIBA, T ;

SAKAI, R ;

KOHMOTO, S ;

SAUCY, G ;

HIGA, T .

TETRAHEDRON LETTERS, 1988, 29 (25) :3083-3086

[5] KERAMAPHIDIN-B, A NOVEL PENTACYCLIC ALKALOID FROM A MARINE SPONGE AMPHIMEDON SP - A PLAUSIBLE BIOGENETIC PRECURSOR OF MANZAMINE ALKALOIDS [J].

KOBAYASHI, J ;

TSUDA, M ;

KAWASAKI, N ;

MATSUMOTO, K ;

ADACHI, T .

TETRAHEDRON LETTERS, 1994, 35 (25) :4383-4386

[6]

KOBAYASHI M, 1994, CHEM PHARM BULL, V42, P2449

[7] IRCINAL-A AND IRCINAL-B FROM THE OKINAWAN MARINE SPONGE-IRCINIA SP - PLAUSIBLE BIOGENETIC PRECURSORS OF MANZAMINE ALKALOIDS [J].

KONDO, K ;

SHIGEMORI, H ;

KIKUCHI, Y ;

ISHIBASHI, M ;

SASAKI, T ;

KOBAYASHI, J .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (08) :2480-2483

[8] INGAMINE-A AND INGAMINE-B, NEW CYTOTOXIC ALKALOIDS FROM THE MARINE SPONGE XESTOSPONGIA-INGENS [J].

KONG, FM ;

ANDERSEN, RJ ;

ALLEN, TM .

TETRAHEDRON, 1994, 50 (21) :6137-6144

[9] PHYSIOLOGICALLY ACTIVE MARINE NATURAL-PRODUCTS FROM PORIFERA .15. KERAMAMINE-A AND KERAMAMINE-B, NOVEL ANTIMICROBIAL ALKALOIDS FROM THE OKINAWAN MARINE SPONGE PELLINA SP [J].

NAKAMURA, H ;

DENG, SZ ;

KOBAYASHI, J ;

OHIZUMI, Y ;

TOMOTAKE, Y ;

MATSUZAKI, T ;

HIRATA, Y .

TETRAHEDRON LETTERS, 1987, 28 (06) :621-624

[10] NOVEL MARINE SPONGE ALKALOIDS ACIDS .7. REVISED STRUCTURE OF XESTOCYCLAMINE-A AND DESCRIPTION OF A NEW ANALOG [J].

RODRIGUEZ, J ;

CREWS, P .

TETRAHEDRON LETTERS, 1994, 35 (27) :4719-4722