SELECTIVE-INHIBITION OF BENZYL ETHER HYDROGENOLYSIS WITH PD/C DUE TO THE PRESENCE OF AMMONIA, PYRIDINE OR AMMONIUM ACETATE

被引：135

作者：

SAJIKI, H

机构：

[1] Metasyn, Inc., Cambridge, MA 02142

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 20期

关键词：

D O I：

10.1016/0040-4039(95)00527-J

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ammonia, pyridine and ammonium acetate were found to be extremely effective as inhibitors of Pd/C catalyzed benzyl ether hydrogenolysis. While olefin, Cbz, benzyl ester and azide functionalities were hydrogenated smoothly, benzyl ethers were not cleaved in the presence of these additives.

引用

页码：3465 / 3468

页数：4

共 11 条

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