MECHANISM OF BLEOMYCIN - EVIDENCE FOR A RATE-DETERMINING 4'-HYDROGEN ABSTRACTION FROM POLY(DA-DU) ASSOCIATED WITH THE FORMATION OF BOTH FREE BASE AND BASE PROPENYL

被引：126

作者：

WU, JC

KOZARICH, JW

STUBBE, J

机构：

[1] YALE UNIV, SCH MED, DEPT PHARMACOL, NEW HAVEN, CT 06510 USA

[2] YALE UNIV, SCH MED, CTR THORAC SURG, DEV THERAPEUT PROGRAM, NEW HAVEN, CT 06510 USA

[3] UNIV WISCONSIN, COLL AGR & LIFE SCI, DEPT BIOCHEM, MADISON, WI 53706 USA

来源：

BIOCHEMISTRY | 1985年 / 24卷 / 26期

关键词：

D O I：

10.1021/bi00347a009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：7562 / 7568

页数：7

相关论文

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[1] BURGER RM, 1981, J BIOL CHEM, V256, P1636
[2] BURGER RM, 1980, J BIOL CHEM, V255, P1832
[3] BURGER RM, 1982, J BIOL CHEM, V257, P8612
[4] COPPER(I)-BLEOMYCIN - STRUCTURALLY UNIQUE COMPLEX THAT MEDIATES OXIDATIVE DNA STRAND SCISSION
EHRENFELD, GM
RODRIGUEZ, LO
HECHT, SM
CHANG, C
BASUS, VJ
OPPENHEIMER, NJ
[J]. BIOCHEMISTRY, 1985, 24 (01) : 81 - 92
[5] A new absorbent for oxygen in gas analysis
Fieser, LF
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1924, 46 : 2639 - 2647
[6] GILONI L, 1981, J BIOL CHEM, V256, P8608
[7] MECHANISM OF INACTIVATION OF ESCHERICHIA-COLI AND LACTOBACILLUS-LEICHMANNII RIBONUCLEOTIDE REDUCTASES BY 2'-CHLORO-2'-DEOXYNUCLEOTIDES - EVIDENCE FOR GENERATION OF 2-METHYLENE-3(2H)-FURANONE
HARRIS, G
ATOR, M
STUBBE, J
[J]. BIOCHEMISTRY, 1984, 23 (22) : 5214 - 5225
[8] CONVERSION OF MONO- AND OLIGODEOXYRIBONUCLEOTIDES TO 5'-TRIPHOSPHATES
HOARD, DE
OTT, DG
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (08) : 1785 - &
[9] PURINE NUCLEOSIDE SYNTHESIS, AN EFFICIENT METHOD EMPLOYING NUCLEOSIDE PHOSPHORYLASES
KRENITSKY, TA
KOSZALKA, GW
TUTTLE, JV
[J]. BIOCHEMISTRY, 1981, 20 (12) : 3615 - 3621
[10] AN ACTIVE INTERMEDIATE FORMED IN THE REACTION OF BLEOMYCIN-FE(II) COMPLEX WITH OXYGEN
KURAMOCHI, H
TAKAHASHI, K
TAKITA, T
UMEZAWA, H
[J]. JOURNAL OF ANTIBIOTICS, 1981, 34 (05) : 576 - 582