LOCALIZATION OF THE HUMAN GENE FOR 230-KDAL BULLOUS PEMPHIGOID AUTOANTIGEN (BPAG1) TO CHROMOSOME 6PTER-]Q15

被引：15

作者：

MINOSHIMA, S

AMAGAI, M

KUDOH, J

FUKUYAMA, R

HASHIMOTO, T

NISHIKAWA, T

SHIMIZU, N

机构：

[1] KEIO UNIV,SCH MED,DEPT MOLEC BIOL,35 SHINANOMACHI,SHINJUKU KU,TOKYO 160,JAPAN

[2] KEIO UNIV,SCH MED,DEPT DERMATOL,TOKYO 160,JAPAN

来源：

CYTOGENETICS AND CELL GENETICS | 1991年 / 57卷 / 01期

关键词：

D O I：

10.1159/000133108

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Chromosome mapping of the human gene encoding the 230-kDal autoantigen of an autoimmune skin disease, bullous pemphigoid, was performed using flow-sorted human chromosomes of cells of normal karyotype and cells carrying a reciprocal translocation t(6;16)(q15;q24). The cDNA of the autoantigen hybridized with intact chromosome 6 and translocation chromosome 6p- (6pter --> 15::16q2 --> qter). The gene (BPA230) was located to the chromosome region 6pter --> q15.

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页码：30 / 32

页数：3

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