IMMUNOGLOBULIN-COMPLEXED ASPARTATE-AMINOTRANSFERASE

被引：7

作者：

MATAMA, S

ITO, H

TANABE, S

SHIBUYA, A

SHIBATA, H

SAIGENJI, K

SAKURAI, K

HASEGAWA, M

机构：

[1] Department of Gastroenterology, Kitasato University East Hospital, Sagamihara

[2] Department of Clinical Laboratory, Kitasato University, East Hospital, Tokyo

来源：

INTERNAL MEDICINE | 1993年 / 32卷 / 02期

关键词：

ATYPICAL AST; IMMUNOGLOBULIN-COMPLEXED ENZYME;

D O I：

10.2169/internalmedicine.32.156

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of increased aspartate aminotransferase (AST, EC 2.6. 1. 1; GOT) in a 17-year-old girl which persisted for 3 years. The patient was healthy, but a high level of serum AST was detected during a school health check. Further examination revealed that AST was increased to as high as 259 IU/l while alanine aminotransferase (ALT) was normal. Immunoelectrosyneresis and immunoprecipitation methods revealed that this atypical AST combined with IgG - kappa, lambda globulin and formed macromolecular complexes. Including the present case, 26 cases of IgG-complexed AST have been reported. It is important to be aware of this syndrome, and thereby avoid unnecessary examinations and therapies.

引用

页码：156 / 159

页数：4

共 9 条

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