METABOLISM OF L-ASCORBIC-4-3H ACID IN MAN

被引：23

作者：

TOLBERT, BM

CHEN, AW

BELL, EM

BAKER, EM

机构：

来源：

AMERICAN JOURNAL OF CLINICAL NUTRITION | 1967年 / 20卷 / 03期

关键词：

D O I：

10.1093/ajcn/20.3.250

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The kinetic and metabolic fate of ascorbic-4-3H acid was studied in a human subject The radioactive label does not enter the body water pool, but instead is excreted as organic-bound tritium. The excretion products were found to be ascorbic acid and its immediate oxidation products, and unknown organic compound(s). Kinetic analysis of the data shows half times of 2 days and 46 days for turnover of the labeled ascorbic acid and the unknown compound, respectively. These results, combined with previous ascorbate-1-14C studies, indicate that the unknown metabolite(s) are probably derivative(s) of L-threose or L-threonic acid.

引用

页码：250 / +

共 6 条

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[2]

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[3] SYNTHESIS OF L-ASCORBIC-4-3H ACID [J].

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BAKER, EM ;

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JOURNAL OF LABELLED COMPOUNDS, 1966, 2 (02) :148-&

[4]

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[5] A SIMPLIFIED METHOD FOR ISOLATION OF URINARY ASCORBIC ACID AS 2,4-DINITROPHENYLOSAZONE [J].

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ANALYTICAL BIOCHEMISTRY, 1966, 15 (03) :537-+

[6]

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