CONSOLIDATION AND MAZE LEARNING - EFFECTS OF POST-TRIAL INJECTIONS OF A DEPRESSANT DRUG (PENTOBARBITAL SODIUM)

Subjects from the Maudsley Reactive and Non-Reactive strains were injected with either pentobarbital sodium or distilled water immediately after a daily trial on problem 4 of the Hebb Williams maze. The experimental group made more errors and took more time than their control groups, over a ten day period. Animals of the Maudsley Reactive strain were superior to those of the Non-Reactive strain. It was suggested that pentobarbital sodium disrupted learning by decreasing the rate of the consolidation process. © 1968 Springer-Verlag.