BLOOD-FLOW MEASUREMENT FROM 1ST PASS TIME ACTIVITY CURVES - INFLUENCE OF BOLUS SPREADING

被引：7

作者：

BELL, SD ^{[1
]}

PETERS, AM ^{[1
]}

机构：

[1] HAMMERSMITH HOSP,DEPT DIAGNOST RADIOL,DU CANE RD,LONDON W12 0NN,ENGLAND

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1990年 / 11卷 / 07期

关键词：

D O I：

10.1097/00006231-199007000-00003

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Organ blood flow as a fraction of cardiac output can be measured from the first pass time/ activity curves recorded over the organ and over 'arterial' regions of interest (ROIs). The right lung, left ventricle and aorta can all be used as the arterial ROI, and separate estimates of blood flow corresponding to each ROI can be derived. Organ blood flow based on the lung ROI was significantly less than that based on the left ventricle in adults, with a mean ratio of 0.94 (S.D.) 14; p < 0.001), but not in children (1.02 (0.13); p > 0.1). Blood flow based on the aorta was greater than that based on the left ventricle in adults and children with respective ratios of 1.05 (0.18; p < 0.01) and 1.08 (0.16; p > 0.05). Because of its clearer definition and relatively later point of recirculation, the lung curve should give the most reliable estimate of blood flow. However, because some bolus spreading occurs between the pulmonary vein and organ (e.g. kidney), organ blood flow based on the lung ROI should be multiplied by 1.06. © 1990 Chapman and Hall Ltd.

引用

页码：477 / 480

页数：4

共 4 条

[1] Peters A.M., Gunasekera R.D., Henderson B.L., Brown J., Lavender J.P., De Sousa M., Ash J.M., Gilday D.L., Non-invasive measurement of blood flow and extraction fraction, Nucl Med Commiin, 8, pp. 823-837, (1987)
[2] Peters A.M., Brown J., Hartnell G.G., Myers M.J., Haskell C., Lavender J.P., Non-invasive measurement of renal blood flow with Tc-99m DTPA: Comparison with radiolabelled microspheres, Cardiovasc Res, 21, pp. 830-834, (1987)
[3] Peters A.M., George P., Brown J., Lavender J.P., Filtration fraction: Non-invasive measuremenl with Tc-99m DTPA and changes induced by angiotensin converting enzyme inhibition in hypertension, Nephron, 51, pp. 470-473, (1989)
[4] Wehrenberg J.C., Becker G.J., Holden R.W., Richmond B.D., Jackson V.P., Yune H.Y., Bendick P.J., Klatte E.C., Influence of cardiac function on the quality of intravenous digital subtraction angiograms, Invest Radiol, 20, pp. 33-35, (1985)

← 1 →