STUDY OF BLOOD COMPATIBLE POLYMERS .3. COPOLYMERS OF N-BENZYL, N-(2-HYDROXYETHYL) ACRYLAMIDE AND 2-HYDROXYETHYL METHACRYLATE

被引：18

作者：

MATHEW, J ^{[1
]}

LIU, SQ ^{[1
]}

KODAMA, M ^{[1
]}

机构：

[1] RES INST POLYMERS & TEXT,DEPT BIOENGN,1-1-4 HIGASHI,TSUKUBA,IBARAKI 305,JAPAN

来源：

BIOMATERIALS | 1993年 / 14卷 / 01期

基金：

日本科学技术振兴机构;

关键词：

COPOLYMERIZATION; PLATELETS; FIBROBLASTS; CELL GROWTH;

D O I：

10.1016/0142-9612(93)90076-E

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Copolymerization of 2-hydroxyethyl methacrylate (HEMA) and N-benzyl, N-(2-hydroxyethyl) acrylamide (BENAAm) was carried out at different mole ratios of the monomers to obtain copolymers of varying composition. BENAAm content of the copolymers varies between 13 and 70%. Investigation of the interaction of rabbit platelets with these polymer surfaces showed that copolymers with higher BENAAm content inhibit the platelet deformation. Human umbilical cord fibroblast cells proliferated very well on the copolymer surfaces. The cell growth rate on polyHEMA was relatively low. Maximum cell growth was observed on the copolymer having 87% HEMA.

引用

页码：57 / 63

页数：7

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