SEROPREVALENCE AND SIGNIFICANCE OF ANTIBODIES TO HEPATITIS-C VIRUS IN PEDIATRIC-PATIENTS WITH MALIGNANT DISEASES

被引：3

作者：

SCHNEPPENHEIM, R ^{[1
]}

RAUTENBERG, P ^{[1
]}

BEHNKE, H ^{[1
]}

VIETOR, K ^{[1
]}

机构：

[1] UNIV KIEL,KINDERKLIN,DEPT MICROBIOL,W-2300 KIEL 1,GERMANY

来源：

KLINISCHE PADIATRIE | 1991年 / 203卷 / 04期

关键词：

D O I：

10.1055/s-2007-1025441

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The prevalence of antibodies to hepatitis C virus recombinant antigen c100-3 was determined in 82 pediatric patients with malignant diseases who received blood transfusions as support during their chemotherapy. By prescreening, 12 of 82 patients were repeatedly positive. No positive correlation was established neither with the number of transfused blood units nor with surrogate markers for hepatitis NANB like ALT or anti HBc. Additional testing by alternate test assays revealed discordant results in 11 of these patients. Possble explanations, like reactivity to test-immanent coexpressed antigens of Saccharomyces cerevisae are discussed.

引用

页码：273 / 275

页数：3

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