IMPROVED ACOUSTIC-PLATE-MODE BIOSENSOR

被引：20

作者：

ANDLE, JC ^{[1
]}

WEAVER, JT ^{[1
]}

MCALLISTER, DJ ^{[1
]}

JOSSE, F ^{[1
]}

VETELINO, JF ^{[1
]}

机构：

[1] UNIV MAINE,SURFACE SCI & TECHNOL LAB,ORONO,ME 04469

来源：

SENSORS AND ACTUATORS B-CHEMICAL | 1993年 / 13卷 / 1-3期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0925-4005(93)85421-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The design of an improved acoustic-plate-mode (APM) biosensor is presented. The biosensing element consists of a pair of APM delay lines fabricated on an ZX lithium niobate (LiNbO3) substrate. Each delay line utilizes a single APM and exhibits adjacent-mode rejection superior to previous LiNbO3 designs, without sacrificing the high sensitivity to electrical effects. The biosensing element is evaluated as an immunosensor using the vector voltmeter (VVM) measurement system. The results show that the improved biosensor is capable of selectively detecting antibody concentrations of 20 ng per ml.

引用

页码：437 / 442

页数：6