SEQUENCE HOMOLOGY BETWEEN PURPLE ACID-PHOSPHATASES AND PHOSPHOPROTEIN PHOSPHATASES - ARE PHOSPHOPROTEIN PHOSPHATASES METALLOPROTEINS CONTAINING OXIDE-BRIDGED DINUCLEAR METAL CENTERS

被引：51

作者：

VINCENT, JB ^{[1
]}

AVERILL, BA ^{[1
]}

机构：

[1] UNIV VIRGINIA, DEPT CHEM, CHARLOTTESVILLE, VA 22901 USA

来源：

FEBS LETTERS | 1990年 / 263卷 / 02期

关键词：

Protein phosphatase; Purple acid phosphatase; Sequence homology;

D O I：

10.1016/0014-5793(90)81389-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The amino acid sequences of mammalian purple acid phosphatases and phosphoprotein phosphatases are shown to possess regions of significant homology. The conserved residues contain a high percentage of possible metal-binding residues. The phosphoprotein phosphatases 1, 2A and 2B are proposed to be iron-zinc metalloenzymes with active sites isostructural (or nearly so) with those of the purple phosphatases. © 1990.

引用

页码：265 / 268

页数：4

共 43 条

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