CHEMICAL SYNTHESIS OF DIMER RIBONUCLEOTIDES CONTAINING INTERNUCLEOTIDIC PHOSPHORODITHIOATE LINKAGES

被引：19

作者：

PETERSEN, KH ^{[1
]}

NIELSEN, J ^{[1
]}

机构：

[1] UNIV COPENHAGEN,HC ORSTED INST,DEPT GEN & ORGAN CHEM,UNIV PK 5,DK-2100 COPENHAGEN,DENMARK

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)94661-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ribonucleosides, chlorobis(amino)phosphines and thiols react via phosphorothioamidites to form phosphorothioites. Oxidation with sulphur gives ribonucleoside phosphorodithioate triesters which after deprotection yields the phosphorodithioate ribonucleoside analogues. © 1990.

引用

页码：911 / 914

页数：4

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