CELL CONTOUR EXTRACTION ON MULTITHRESHOLD IMAGES

被引：6

作者：

BARBA, J

YUAN, L

GIL, J

机构：

[1] MT SINAI MED CTR NEW YORK, DEPT PATHOL, 1 GUSTAVE L LEVY PL, NEW YORK, NY 10029 USA

[2] CUNY CITY COLL, DEPT ELECT ENGN, NEW YORK, NY 10031 USA

来源：

PATHOLOGY RESEARCH AND PRACTICE | 1992年 / 188卷 / 4-5期

关键词：

CONTOUR EXTRACTION; SEGMENTATION; MULTITHRESHOLDING;

D O I：

10.1016/S0344-0338(11)80036-1

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

A procedure for the extraction of cell and nuclear contours from digital images is presented. The procedure is simple and suitable for efficient implementation in an interactive environment where the user selects a region of interest containing the cell to be segmented. Segmentation is facilitated by multi-thresholding where the threshold values are determined by an iterative algorithm using the mean square error criteria to cluster the image pixel values. Edges are detected on the threshold images by employing a binary morphological filter and the desired contours are selected by considering closed contours in the edge image. The cell region is first extracted by performing segmentation, edge detection and contour extraction on the region of interest. The nuclear region is subsequently extracted by reapplication of the algorithms within the extracted cell region. Segmentation examples are presented.

引用

页码：449 / 453

页数：5

共 10 条

[1]

BARBA J, 1992, IN PRESS J ELECT MIC

[2] ON THE STRUCTURE OF VECTOR QUANTIZERS [J].

GERSHO, A .

IEEE TRANSACTIONS ON INFORMATION THEORY, 1982, 28 (02) :157-166

[3]

Gray R. M., 1984, IEEE ASSP Magazine, V1, P4, DOI 10.1109/MASSP.1984.1162229

[4]

JEANTY H, 1987, ACTA STEREOL, V6, P233

[5] ALGORITHM FOR VECTOR QUANTIZER DESIGN [J].

LINDE, Y ;

BUZO, A ;

GRAY, RM .

IEEE TRANSACTIONS ON COMMUNICATIONS, 1980, 28 (01) :84-95

[6] COMPUTERIZED INTERACTIVE MORPHOMETRY IN PATHOLOGY - CURRENT INSTRUMENTATION AND METHODS [J].

MARCHEVSKY, AM ;

GIL, J ;

JEANTY, H .

HUMAN PATHOLOGY, 1987, 18 (04) :320-331

[7]

Pavlidis T., 1982, ALGORITHMS GRAPHICS

[8]

RAMAMOORTHHY PA, 1986, HYBRID CODING INVOLV

[9]

VLADIMIR C, 1985, IEEE T COMMUN, V33, P685

[10]

YUAN L, 1990, SPIE C, V1349

← 1 →