THE EFFECT OF EGB-761 ON RETINAL LIPID-PEROXIDATION AND GLUTATHIONE-PEROXIDASE LEVEL IN EXPERIMENTAL LENS-INDUCED UVEITIS

被引：9

作者：

BILGIHAN, A ^{[1
]}

ARICIOGLU, A ^{[1
]}

BILGIHAN, K ^{[1
]}

ONOL, M ^{[1
]}

HASANREISOGLU, B ^{[1
]}

TURKOZKAN, N ^{[1
]}

机构：

[1] GAZI UNIV,FAC MED,DEPT OPHTHALMOL,ANKARA,TURKEY

来源：

INTERNATIONAL OPHTHALMOLOGY | 1994年 / 18卷 / 01期

关键词：

EGB; 761; GLUTATHIONE PEROXIDASE; LENS INDUCED UVEITIS; LIPID PEROXIDATION; PIGMENTED GUINEA PIGS;

D O I：

10.1007/BF00919409

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

An acute lens-induced necrotizing intraocular inflammation was produced in pigmented guinea pigs. Treatment of these animals by 100 mg/kg/day EGb 761 a free oxygen radical scavenger for 10 days, reduced retinal lipid peroxidation (p > 0.05) and increased the retinal glutathione peroxidase level (p > 0.05). Although not significantly, these findings suggest that EGb 761 could be combined with other antiinflammatory drugs and may be beneficial in the treatment of uveitis.

引用

页码：21 / 24

页数：4

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