THE STR SYSTEM HTPO - POPULATION AND SEGREGATION DATA

被引：17

作者：

GUSMAO, L

PRATA, MJ

AMORIM, A

机构：

[1] Instituto Antropologia, University Porto, Porto, P-4050, Pr. Gomes Teixeira

来源：

INTERNATIONAL JOURNAL OF LEGAL MEDICINE | 1995年 / 108卷 / 03期

关键词：

HTPO; STR; POPULATION GENETICS; PATERNITY INVESTIGATIONS;

D O I：

10.1007/BF01844832

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A population study was carried out on a random sample of 164 individuals from North Portugal using the short tandem repeat (STR) system hTPO (locus: 2p23-2pter). After electrophoresis, 7 alleles were identified of which 6 had been previously described and a new one, estimated to be 134 bp long. The observed genotype distribution is in Hardy-Weinberg equilibrium. In order to assess the forensic applicability of the system, namely for paternity investigations, 109 mother-child pairs were analysed. No exclusions were found and the observed distribution did not deviate from the expected. Since hTPO has a relatively high information content (PIC = 0.60; H = 0.65) this system can be very useful in paternity investigations.

引用

页码：167 / 169

页数：3

共 8 条

[1] Anker R., 1992, Human Molecular Genetics, V1, P137, DOI 10.1093/hmg/1.2.137
[2] BUDOWLE B, 1991, AM J HUM GENET, V48, P137
[3] PERFORMING THE EXACT TEST OF HARDY-WEINBERG PROPORTION FOR MULTIPLE ALLELES
GUO, SW
THOMPSON, EA
[J]. BIOMETRICS, 1992, 48 (02) : 361 - 372
[4] CHINESE POPULATION-DATA ON 3 TETRAMERIC SHORT TANDEM REPEAT LOCI - HUMTHO1, TPOX, AND CSF1PO - DERIVED USING MULTIPLEX PCR AND MANUAL TYPING
HUANG, NE
SCHUMM, J
BUDOWLE, B
[J]. FORENSIC SCIENCE INTERNATIONAL, 1995, 71 (02) : 131 - 136
[5] INVESTIGATION OF THE STR LOCUS HUMTH01 USING PCR AND 2 ELECTROPHORESIS FORMATS - UK AND GALICIAN CAUCASIAN POPULATION SURVEYS AND USEFULNESS IN PATERNITY INVESTIGATIONS
LAREU, MV
PHILLIPS, CP
CARRACEDO, A
LINCOLN, PJ
COURT, DS
THOMSON, JA
[J]. FORENSIC SCIENCE INTERNATIONAL, 1994, 66 (01) : 41 - 52
[6] LUIS JR, 1995, IN PRESS HUM BIOL
[7] URQUHART A, 1994, INT J LEGAL MED, V106, P183
[8] 1994, INT J LEGAL MED, V107, P159

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