ANOMALY IN THE MODIFIED MOSHER METHOD - ABSOLUTE-CONFIGURATIONS OF SOME MARINE CEMBRANOLIDES

被引：99

作者：

KUSUMI, T ^{[1
]}

FUJITA, Y ^{[1
]}

OHTANI, I ^{[1
]}

KAKISAWA, H ^{[1
]}

机构：

[1] UNIV TSUKUBA,DEPT CHEM,SAKURA,IBARAKI 305,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 25期

关键词：

D O I：

10.1016/0040-4039(91)80650-U

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Utility of the modified Mosher's method is examined by applying it to three marine cembranolides, 2, 3, and 4, with known absolute configurations, and it is concluded that the method can be safely used for the compounds with a sterically unhindered OH group, but care must be taken in applying it to the secondary alcohols with the OH group located in a crowded environment.

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页码：2923 / 2926

页数：4

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